Brooks Glycerin 22 Shoe - Women's

Soft, supportive Glycerin 22 for cushioned, smooth women’s road running

What Our Gearhead® Experts Are Saying: "The Glycerin 22 has unbeatable cushioning that’s perfect for longer runs. It’s so soft underfoot, and the fit is really secure without feeling tight. I love how the DNA LOFT cushioning helps with shock absorption, making it a great choice for anyone who wants a smooth, comfortable ride."

Engineered for women who love a plush, cushioned ride, the Brooks Glycerin 22 Running Shoe provides ultimate comfort for road running. With DNA LOFT cushioning throughout, this shoe absorbs impact smoothly, creating a soft and consistent feel that holds up mile after mile. The engineered mesh upper enhances airflow and provides a secure yet flexible fit, ensuring all-day comfort and stability for long-distance training and recovery runs alike.

With a full-length cushioned sole, the Glycerin 22 offers optimal shock absorption and energy return, making it an ideal choice for road runners who seek comfort and support. Its durable outsole and snug fit ensure this shoe is ready for frequent use, providing a luxuriously smooth experience on every run.

Details

Soft, responsive ride for long runs, recovery days, and runners who prioritize softness
Engineered mesh upper offers breathability and a secure, adaptive fit
Full-length cushioned sole provides consistent comfort and impact absorption
Snug, seamless design keeps the foot stable and supported over long distances
Durable outsole enhances longevity for frequent road use
Designed for women who want maximum comfort and support in their running shoe
Item #BRJG0BK

Upper Material: synthetic
Closure: lace
Midsole: DNA LOFT
Sole: rubber
Cushion: maximum
Activity: road running

Reviews

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Overall Rating

4 based on 494 ratings

Review Summary

1 Stars - 46 reviews

2 Stars - 37 reviews

3 Stars - 60 reviews

4 Stars - 61 reviews

5 Stars - 290 reviews

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Here's what customers have to say

The Glycerin 22 is a well-cushioned and comfortable running and walking shoe. Reviewers praised the high level of cushioning and support, describing the shoes as feeling like "walking on clouds" with excellent shock absorption. Many noted the shoes were comfortable right out of the box. The shoes are described as responsive and springy, providing a propulsive feel. However, some reviewers felt the shoes were too soft and lacked stability, especially for those needing more arch support. A few also found the toe box to be too narrow compared to previous models, and some recommended sizing up.

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2 out of 5 stars

August 27, 2025

Buckling/denting.

As a bedside nurse, Glycerins have been my go-to’s since 2017. The 22’s have been such a disappointment. The toe boxes began buckling/denting with movement. The inner left toe dent is rubbing against my toe causing sharp pain. I’ve given them 3 weeks to see if they’ll break in and the buckling remains the same. So disappointing. Anyone have any recs (brooks or other good athletic shoe brands) similar to the comfort of prior Glycerins? Thanks in advance!